The 12th International Conference on Information Technology and Knowledge  was  held in collaboration with the Mazandaran University of Science and Technology and the Information and Communication Technology Association of Iran on 14-16​​December 2021. 

126 papers were sent to the conference secretariat, of which 64 papers were finally accepted and presented in 11 conference sessions.

Professor Kambiz Badie, a member of the faculty of the Institute of Information and Communication Technology, Dr. Nematollah Shiri from Concordia University, and Dr. Mohammad Ali Akhaei, Associate Professor of Intelligence, Machine, and Robotics from the University of Tehran, were keynote speakers at the conference.